In situ detection of H2O2 in mouse neocortex and cerebellum was carried out by exploiting the fluorogenic peroxidase substrate AUR (Amplex UltraRed reagent, Invitrogen) that reacts in a one:1 stoichiometry with H2O2 to produce a very fluorescent reaction product (excitation/emission maxima around 568/ 581 nm)
All double transgenic animals JoSMOrec have been acquired from a cross in between JoSMO...