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E. Part of his explanation for the error was his willingness to capitulate when tired: `I did not ask for any health-related history or something like that . . . more than the phone at 3 or four o’clock [in the morning] you just say yes to anything’ pnas.1602641113 Interviewee 25. In spite of sharing these related characteristics, there have been some variations in error-producing conditions. With KBMs, medical doctors have been conscious of their information deficit at the time of your prescribing decision, in contrast to with RBMs, which led them to take among two pathways: approach other folks for314 / 78:2 / Br J Clin PharmacolLatent conditionsSteep hierarchical structures inside medical teams prevented medical doctors from in search of enable or indeed getting adequate assistance, highlighting the importance from the prevailing medical culture. This varied among specialities and accessing tips from seniors appeared to be more problematic for FY1 trainees working in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for guidance to stop a KBM, he felt he was Pictilisib annoying them: `Q: What created you believe that you simply could be annoying them? A: Er, just because they’d say, you realize, 1st words’d be like, “Hi. Yeah, what’s it?” you know, “I’ve scrubbed.” That’ll be like, kind of, the introduction, it would not be, you understand, “Any complications?” or something like that . . . it just does not sound pretty approachable or friendly on the telephone, you understand. They just sound rather direct and, and that they were busy, I was inconveniencing them . . .’ Interviewee 22. Health-related culture also influenced doctor’s behaviours as they acted in strategies that they felt have been essential so that you can fit in. When exploring doctors’ factors for their KBMs they discussed how they had chosen to not seek guidance or information for worry of looking incompetent, particularly when new to a ward. Interviewee two under explained why he did not verify the dose of an antibiotic despite his uncertainty: `I knew I should’ve looked it up cos I didn’t genuinely know it, but I, I believe I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was one thing that I should’ve known . . . since it is quite simple to have caught up in, in getting, you understand, “Oh I’m a Doctor now, I know stuff,” and with all the pressure of folks who’re perhaps, kind of, a little bit more senior than you considering “what’s incorrect with him?” ‘ Interviewee two. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent condition as an alternative to the actual culture. This interviewee discussed how he ultimately discovered that it was acceptable to check details when prescribing: `. . . I come across it pretty good when Consultants open the BNF up in the ward rounds. And you believe, well I’m not supposed to know just about every single medication there is, or the dose’ Interviewee 16. Healthcare culture also played a role in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior medical doctors or experienced nursing staff. A great example of this was offered by a doctor who felt relieved when a senior colleague came to assist, but then prescribed an antibiotic to which the patient was allergic, regardless of getting already noted the allergy: `. journal.pone.0169185 . . the Registrar came, purchase STA-9090 reviewed him and stated, “No, no we must give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it on the chart without having considering. I say wi.E. A part of his explanation for the error was his willingness to capitulate when tired: `I did not ask for any medical history or something like that . . . over the telephone at 3 or four o’clock [in the morning] you simply say yes to anything’ pnas.1602641113 Interviewee 25. Regardless of sharing these equivalent traits, there were some differences in error-producing circumstances. With KBMs, medical doctors were aware of their information deficit in the time on the prescribing choice, as opposed to with RBMs, which led them to take one of two pathways: approach other folks for314 / 78:2 / Br J Clin PharmacolLatent conditionsSteep hierarchical structures within health-related teams prevented physicians from looking for enable or certainly receiving sufficient aid, highlighting the importance on the prevailing medical culture. This varied between specialities and accessing suggestions from seniors appeared to be far more problematic for FY1 trainees working in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for guidance to stop a KBM, he felt he was annoying them: `Q: What produced you feel that you simply could be annoying them? A: Er, simply because they’d say, you know, 1st words’d be like, “Hi. Yeah, what is it?” you understand, “I’ve scrubbed.” That’ll be like, kind of, the introduction, it wouldn’t be, you realize, “Any challenges?” or anything like that . . . it just does not sound very approachable or friendly around the phone, you understand. They just sound rather direct and, and that they were busy, I was inconveniencing them . . .’ Interviewee 22. Healthcare culture also influenced doctor’s behaviours as they acted in ways that they felt were essential in order to match in. When exploring doctors’ motives for their KBMs they discussed how they had selected to not seek assistance or details for worry of seeking incompetent, particularly when new to a ward. Interviewee 2 beneath explained why he did not verify the dose of an antibiotic in spite of his uncertainty: `I knew I should’ve looked it up cos I did not truly know it, but I, I feel I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was some thing that I should’ve known . . . since it is quite easy to acquire caught up in, in getting, you know, “Oh I am a Medical doctor now, I know stuff,” and together with the pressure of folks that are maybe, sort of, a little bit bit much more senior than you pondering “what’s wrong with him?” ‘ Interviewee two. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent condition as an alternative to the actual culture. This interviewee discussed how he sooner or later discovered that it was acceptable to check facts when prescribing: `. . . I discover it pretty nice when Consultants open the BNF up in the ward rounds. And you feel, effectively I’m not supposed to know every single medication there’s, or the dose’ Interviewee 16. Health-related culture also played a part in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior doctors or skilled nursing employees. A good example of this was offered by a physician who felt relieved when a senior colleague came to help, but then prescribed an antibiotic to which the patient was allergic, in spite of obtaining currently noted the allergy: `. journal.pone.0169185 . . the Registrar came, reviewed him and mentioned, “No, no we really should give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it around the chart without the need of thinking. I say wi.

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