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Tabolites. These SNP werewith a false discovery rateall porcine chromosomes. GWA research revealedSNPs showed a chromosome-wide significance levels of q traits, includingSNP 4 hundred thirty a single 871 (with out double counting) considerable associations for 15 0.05 but no drip loss, 3 proteins and 11 metabolites. These SNP were distributed more than practically all porcine was detected as genome-wide substantial (q 0.01). chromosomes. 4 hundred thirty one SNPs showed a chromosome-wide significance levels of q The average number of significant SNPs per trait was 66, using a minimum of two SNPs 0.05 but no SNP was detected as genome-wide important (q 0.01). (for glucose)averagemaximum of 249 SNPs for fructose-1,6-biphosphatase-2 (FBPase). SNPsmajority in addition to a quantity of considerable SNPs per trait was 66, using a minimum of two The (for The of the SNPs and asignificant of 249 SNPs for chromosome-wide level (q 0.1). The highest proportion glucose) was maximum at a moderate fructose-1,6-biphosphatase-2 (FBPase). The majority of the of explained variance was aobserved for SNPs that affected glucosylceramide, dihydroxyacetone SNPs was important at moderate chromosome-wide level (q 0.1). The highest proportion of phosphate (glycerone-p) and D-glycerate-3-phosphate (DG3P). Essentially the most important SNPs had been explained variance was observed for SNPs that affected glucosylceramide, dihydroxyacetone detected for metabolite hydroxylpyruvic acid (q two.19 10-2 ). The most substantial SNPs have been phosphate (glycerone-p) and D-glycerate-3-phosphate (DG3P). detected for metabolite hydroxylpyruvic acid (q 2.19 10-2). The average quantity of detected SNPs per chromosome is 67 plus the highest numbers from the typical detected on Sus scrofa chromosome (SSC) 14, 67 along with the highest numbers of significant SNPs werenumber of detected SNPs per chromosome is17 and 18. For drip loss, we detected considerable 16 and 18, which clarify a maximum of variance 14, 17 and 18. For drip loss, we the SNPs on SSC SNPs were detected on Sus scrofa chromosome (SSC) proportion of eight.8 . Primarily based on detected SNPs on SSC 16 and 18, SNPs around the a maximum of variance proportion in the Primarily based distance to neighboring significant which explain chromosome (1 Mb), we condensed8.8 .SNPs into on the distance to neighboring 330 significant QTL regions with significant SNPs PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21366670 around the chromosome (1 Mb), we condensed the SNPs an average of 29 QTL per chromosome (Table 3). into 330 critical QTL regions with an typical of 29 QTL per chromosome (Table 3). On various chromosomes we identified 126 (45) SNPs (QTL) which had been considerable for more On quite a few chromosomes we identified 126 (45) SNPs (QTL) which had been considerable for much more than a single trait. These SNPs are positioned on SSC 1, 7, eight, 14, 17 and 18. As presented in Figure 1 one of the most than 1 trait. These SNPs are situated on SSC 1, 7, 8, 14, 17 and 18. As presented in Figure 1 essentially the most overlapping exists among metabolites hydroxypyruvicacid and succinic acid on on SSC Additionally, overlapping exists between metabolites hydroxypyruvic acid and succinic acid SSC 14. 14. Moreover, the overlapping on on SSC 18 is of particularinterest, since it indicates a metabolic process comprising the overlapping SSC 18 is of particular interest, because it indicates a metabolic method comprising buy BRD7552 glycine and phosphoglycerate mutase22(PGAM2) that influences drip loss (Figure 1). On SSC 7, there 7, glycine and phosphoglycerate mutase (PGAM2) that influences drip loss (Figure 1). On SSC.

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