Boc-NH-PEG12-COOH

Supplementary Information:
CAS No.： 1415981-79-1 Synonyms： t-Boc-NH-amido-PEG12-COOH Purity： ≥95% MF： C32H63NO16 MW： 717.8411 Recommended Storage Condition： Store at -5°C,keep in dry and avoid sunlight. Uses： Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Boc-NH-PEG12-COOH, also referred to as t-Boc-N-Amido-PEG12-acid, is a PEG derivative consisting of a Boc-protected amine group (NH) at one end and a carboxylic acid group (COOH) at the other end. The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine, which can undergo amide coupling with carboxylic acid bearing biomolecules.