DSPE-PEG-DBCO

Supplementary Information:
CAS No.： 2052955-83-4 Synonyms： DSPE-PEG-Dibenzocycolctyne Purity： ≥95% Recommended Storage Condition： Store at -5°C,keep in dry and avoid sunlight. Uses： Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. DSPE-PEG-DBCO is a linear heterobifunctional PEG reagent composed of a DSPE phospholipid and a dibenzocyclooctyne (DBCO) group. DSPE-PEG-DBCO enables Cu-free click chemistry reactions due to the reactivity of the DBCO group with azide-functionalized molecules. This bioorthogonal reaction proceeds rapidly under mild physiological conditions, facilitating efficient conjugation without the need for metal catalysts. Additionally, DSPE derivatives provide stability and structural integrity to liposomal formulations, making DSPE-PEG-DBCO particularly suitable for drug delivery systems and nanoparticle functionalization.