DSPE-PEG-NH2

Supplementary Information:
CAS No.： 474922-26-4 Synonyms： DSPE-PEG-Amine Purity： ≥95% Recommended Storage Condition： Store at -5°C,keep in dry and avoid sunlight. Uses： Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. DSPE-PEG-NH2 is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and an amine. DSPE-PEG-NH2 is used to modify liposome surface with biomolecules containing amine reactive groups (NHS, thiolate). It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an amine group for bioconjugation. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the amine group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide.