DSPE-PEG-SC

Supplementary Information:
Synonyms： DSPE-PEG-NHS Purity： ≥95% Recommended Storage Condition： Store at -5°C,keep in dry and avoid sunlight. Uses： Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. ​DSPE-PEG-SC, also known as DSPE-PEG-NHS, is a lipid-based PEG derivative commonly used in the formulation of liposomes and other lipid-based drug delivery systems. It contains succinimidyl ester groups, which are reactive toward primary amines, enabling conjugation with various targeting molecules such as antibodies, aptamers, proteins, and peptides. These targeting molecules are often employed to deliver drugs specifically to target cells or tissues, enhancing therapeutic efficacy while reducing off-target effects. By incorporating DSPE-PEG-SC into liposomal formulations, it helps extend circulating half-life, reduce non-specific protein binding, and minimize cell adhesion, resulting in improved drug delivery efficiency and enhanced therapeutic outcomes.