Product Name :
SQ-31765
Description:
SQ-31765 is a benzazepine calcium channel blocker.
CAS:
138383-07-0
Molecular Weight:
464.48
Formula:
C24H27F3N2O4
Chemical Name:
(3R,4S)-1-[2-(dimethylamino)ethyl]-4-(4-methoxyphenyl)-2-oxo-6-(trifluoromethyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl acetate
Smiles :
CN(C)CCN1C2=CC=CC(=C2C[C@H]([C@@H](OC(C)=O)C1=O)C1C=CC(=CC=1)OC)C(F)(F)F
InChiKey:
GZJHZWDNNABIOE-PGRDOPGGSA-N
InChi :
InChI=1S/C24H27F3N2O4/c1-15(30)33-22-18(16-8-10-17(32-4)11-9-16)14-19-20(24(25,26)27)6-5-7-21(19)29(23(22)31)13-12-28(2)3/h5-11,18,22H,12-14H2,1-4H3/t18-,22+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
SQ-31765 is a benzazepine calcium channel blocker.|Product information|CAS Number: 138383-07-0|Molecular Weight: 464.48|Formula: C24H27F3N2O4|Chemical Name: (3R,4S)-1-[2-(dimethylamino)ethyl]-4-(4-methoxyphenyl)-2-oxo-6-(trifluoromethyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl acetate|Smiles: CN(C)CCN1C2=CC=CC(=C2C[C@H]([C@@H](OC(C)=O)C1=O)C1C=CC(=CC=1)OC)C(F)(F)F|InChiKey: GZJHZWDNNABIOE-PGRDOPGGSA-N|InChi: InChI=1S/C24H27F3N2O4/c1-15(30)33-22-18(16-8-10-17(32-4)11-9-16)14-19-20(24(25,26)27)6-5-7-21(19)29(23(22)31)13-12-28(2)3/h5-11,18,22H,12-14H2,1-4H3/t18-,22+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Islatravir Autophagy |Shelf Life: ≥12 months if stored properly.Lapatinib In stock |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32009350 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|SQ-31765 (SQ 31,765) can reduce the severity of ischemia in a manner which is independent of changes in myocardial blood flow or hemodynamic alterations. Anesthetized dogs are given saline (n=6), SQ-31765 (n=6; 0.2 mg/kg) or SQ 32,189 (n=6; 0.2 mg/kg) i.v. 10 min before ischemia. The effect on pacing-induced ST-segment elevation (pacing+left anterior descending coronary artery stenosis) and myocardial blood flow are determined. SQ-31765 reduces ST-elevation (PProducts are for research use only. Not for human use.|
