Product Name :
MSOP
Description:
MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR.
CAS:
66515-29-5
Molecular Weight:
199.10
Formula:
C4H10NO6P
Chemical Name:
(2R)-2-amino-2-methyl-3-(phosphonooxy)propanoic acid
Smiles :
C[C@@](N)(COP(O)(O)=O)C(O)=O
InChiKey:
GSFCOAGADOGIGE-SCSAIBSYSA-N
InChi :
InChI=1S/C4H10NO6P/c1-4(5,3(6)7)2-11-12(8,9)10/h2,5H2,1H3,(H,6,7)(H2,8,9,10)/t4-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR.Luminol medchemexpress |Product information|CAS Number: 66515-29-5|Molecular Weight: 199.10|Formula: C4H10NO6P|Chemical Name: (2R)-2-amino-2-methyl-3-(phosphonooxy)propanoic acid|Smiles: C[C@@](N)(COP(O)(O)=O)C(O)=O|InChiKey: GSFCOAGADOGIGE-SCSAIBSYSA-N|InChi: InChI=1S/C4H10NO6P/c1-4(5,3(6)7)2-11-12(8,9)10/h2,5H2,1H3,(H,6,7)(H2,8,9,10)/t4-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 19 mg/mL (95.Bosutinib Protocol 43 mM; Need ultrasonic and warming).PMID:32119330 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|In the presence of 200 μM MSOP, a rightward parallel shift of the dose-response curve to L-AP4 is observed, with an apparent KD calculated as 51±6 μM (n=3). MSOP is shown to be selective for the L-APC sensitive presynaptic mGluR, the apparent KD for the interaction of MSOP with the (1S, 3S)-ACPD sensitive receptor calculated as greater than 700 μM (n=3).|In Vivo:|It is found that TBOA-induced antinociceptive effects are significantly blocked by intrathecal co-administration of MSOP (second phase of formalin model: F3,16=30.96, PProducts are for research use only. Not for human use.|
