Product Name :
D-Erythro-dihydrosphingosine
Description:
D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.
CAS:
764-22-7
Molecular Weight:
301.51
Formula:
C18H39NO2
Chemical Name:
(2S,3R)-2-aminooctadecane-1,3-diol
Smiles :
CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO
InChiKey:
OTKJDMGTUTTYMP-ZWKOTPCHSA-N
InChi :
InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.|Product information|CAS Number: 764-22-7|Molecular Weight: 301.51|Formula: C18H39NO2|Chemical Name: (2S,3R)-2-aminooctadecane-1,3-diol|Smiles: CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO|InChiKey: OTKJDMGTUTTYMP-ZWKOTPCHSA-N|InChi: InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 10 mg/mL (33.Hoechst 33342 medchemexpress 17 mM; ultrasonic and warming and heat to 60°C).Atrasentan GPCR/G Protein |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33316085 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|D-Erythro-dihydrosphingosine (D-erythro-DHS) significantly inhibits mastoparan-, but not Na3VO4-, stimulated arachidonic acid release in PC12 cells. D-Erythro-dihydrosphingosine at 100 AM slightly inhibits [3H]Arachidonic acid release, and 5 μM Ionomycin alone stimulates the release significantly. In the presence of 5 μM Ionomycin, 100 μM C2-ceramide stimulates the release, but D-Erythro-dihydrosphingosine (100 μM) inhibits the release. D-Erythro-dihydrosphingosine inhibits arachidonic acid release in cells and/or cPLA2α activity.|Products are for research use only. Not for human use.|
